drugset / Trial / NCT00158834

Pediatric Asthma Study Using Stepwise Treatment With Two Food And Drug Administration Approved Asthma Medications

NCT00158834

Phase 3 Completed 200 enrolled GlaxoSmithKline
RandomizedParallel-groupDouble-blindTreatment

Summary

This study was designed to evaluate if, in children with asthma, a stepwise treatment (five levels varying from once daily fluticasone propionate 100mcg until twice daily a fixed combination of salmeterol and fluticasone propionate 50/500 mcg) based on symptom scores alone results in a sub-optimal treatment when compared to treatment based on cumulative symptom scores and bronchial hyperresponsiveness (PD20 methacholine).

Timeline

Start
1999-11
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluticasone propionate Other / unclassified
Subject Salmeterol/Fluticasone propionate Unknown

Indications