drugset

drugset / Trial / NCT00159614

Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment

NCT00159614 ↗

Phase 2 Completed 30 enrolled Merck & Co., Inc. Merck Sharp & Dohme LLC · collab

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to characterize the safety and tolerability of KW-3902IV and measure its effect on renal function.

Timeline

Start: 2005-09
Primary completion: —
Completion: —

Publications

Dittrich HC, Gupta DK, Hack TC, Dowling T, Callahan J, Thomson S. The effect of KW-3902, an adenosine A1 receptor antagonist, on renal function and renal plasma flow in ambulatory patients with heart failure and renal impairment. J Card Fail. 2007 Oct;13(8):609-17. doi: 10.1016/j.cardfail.2007.08.006.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	rolofylline	Small molecule	—	Intravenous

Indications