Safety and Efficacy Study of a New Chemotherapy Agent to Treat Non-small-cell Lung Cancer

Summary

Phase 2 study to investigate the efficacy and tolerability of epothilone ZK 219477 in patients with stage IIIb or stage IV non-small-cell lung cancer.

Timeline

Start

2005-08

Primary completion

2008-04

Completion

2009-04

Outcome

Missed primary endpoint

paper the primary endpoint was not achieved. PMID 23522488 ↗

Publications

• Results Heigener DF, von Pawel J, Eschbach C, Brune A, Schmittel A, Schmelter T, Reck M, Fischer JR. Prospective, multicenter, randomized, independent-group, open-label phase II study to investigate the efficacy and safety of three regimens with two doses of sagopilone as second-line therapy in patients with stage IIIB or IV non-small-cell lung cancer. Lung Cancer. 2013 Jun;80(3):319-25. doi: 10.1016/j.lungcan.2013.02.007. Epub 2013 Mar 20.

Drugs

Indications