drugset / Trial / NCT00160342

Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes

NCT00160342

Phase 2 Completed 1251 enrolled Solvay Pharmaceuticals
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a research study to evaluate the effectiveness, safety and side effects of several dose levels of esterified estrogens (EE) and methyltestosterone (MT) given individually and in combination compared to a placebo (a tablet with no active drug in it) as a possible treatment for vasomotor symptoms (such as hot flushes and flushing) of menopause. EE and testosterone are two hormones which are typically deficient in menopausal women

Timeline

Start
2005-06
Primary completion
2007-09
Completion
2007-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator ESTROGENS, ESTERIFIED Unknown 0.15 unknown Oral
Comparator ESTROGENS, ESTERIFIED Unknown 0.3 unknown Oral
Comparator ESTROGENS, ESTERIFIED Unknown 0.45 unknown Oral
Comparator methyltestosterone Small molecule 0.15 unknown Oral
Comparator methyltestosterone Small molecule 0.3 unknown Oral
Comparator methyltestosterone Small molecule 0.6 unknown Oral

Indications

No indication recorded.