drugset / Trial / NCT00162383
Metabolic Capacity of Israeli Populations
NaSingle-groupOpen-labelOther
Summary
The ability to metabolize drugs varies greatly among individuals. Major fraction of this variability lies in genetic polymorphisms of genes encoding for enzymes responsible for both phase I and phase II reactions. The purpose of this study ws to evaluate the phenotypic activity and the frequency of genetic polymorphisms in different phase II and phase I enzymes among various populations residing in Israel.
Timeline
- Start
- 1995-07
- Primary completion
- 2020-12
- Completion
- 2020-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Caffeine | Small molecule | — | — |
| Background | DEBRISOQUIN | Small molecule | — | — |
| Background | Dapsone | Small molecule | — | — |
| Background | Mephenytoin | Small molecule | — | — |
Indications
No indication recorded.