drugset

drugset / Trial / NCT00162955

Prevention of CHOP-induced Chronic Cardiotoxicity

NCT00162955 ↗

Phase 4 Completed 150 enrolled Osaka City University

RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to assess the protective effect of Valsartan on chronic cardiotoxicity induced by CHOP.

Timeline

Start: 2004-05
Primary completion: 2010-09
Completion: 2010-09

Publications

Background Toko H, Oka T, Zou Y, Sakamoto M, Mizukami M, Sano M, Yamamoto R, Sugaya T, Komuro I. Angiotensin II type 1a receptor mediates doxorubicin-induced cardiomyopathy. Hypertens Res. 2002 Jul;25(4):597-603. doi: 10.1291/hypres.25.597.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Valsartan	Small molecule	80 mg	Oral

Indications