Efficacy and Safety of Valsartan Versus Placebo on Exercise Tolerance in Patients With Heart Failure

Summary

This study will test the effects of valsartan versus placebo on exercise tolerance in patients with symptoms of heart failure

Timeline

Start

2002-12

Primary completion

2007-08

Completion

2008-02

Outcome

Missed primary endpoint

paper Valsartan had no significant effect on exercise time (primary variable), PMID 19789402 ↗

Publications

• Results Parthasarathy HK, Pieske B, Weisskopf M, Andrews CD, Brunel P, Struthers AD, MacDonald TM. A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fraction. Eur J Heart Fail. 2009 Oct;11(10):980-9. doi: 10.1093/eurjhf/hfp120.

Drugs

Indications