Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy

Phase 3 Terminated 30 enrolled Pfizer

Non-randomizedSingle-groupOpen-labelTreatment

Summary

* To assess the effect of a long-term treatment by Genotonorm on linear growth in children with short stature receiving steroid therapy * To assess the effect of a long term treatment with Genotonorm on bone mineralisation * To assess the effect of a long term treatment with Genotonorm on body composition

Timeline

Start: 2000-09
Primary completion: 2011-09
Completion: 2011-09

Publications

David H, Aupiais C, Louveau B, Quartier P, Jacqz-Aigrain E, Carel JC, Simon D. Growth Outcomes After GH Therapy of Patients Given Long-Term Corticosteroids for Juvenile Idiopathic Arthritis. J Clin Endocrinol Metab. 2017 Dec 1;102(12):4578-4587. doi: 10.1210/jc.2017-01455.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Somatropin	Protein / enzyme biologic	0.46 mg/kg	—

Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy

Summary

Timeline

Publications

Drugs

Indications