Dynamic Measures of Neurochemistry in Mood Disorders

Summary

The purpose of this study is to understand changes in brain chemical signals when people take antidepressants called sertraline (Zoloft®) and bupropion (Wellbutrin SR, Zyban ®). Spinal fluid is used to measure chemical levels of dopamine, serotonin, and other chemicals thought to be involved in depression. The study has potential to help understand and treat depression.

Timeline

Start

2002-10

Primary completion

2013-04

Completion

2013-04

Drugs

Indications