Risperidone (Risperdal) Augmentation in Depressed Partial Responders to SRI Treatment

Phase 4 Withdrawn Vanderbilt University Medical Center Janssen, LP · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a study of the chemistry of depression in people who are taking an antidepressant but it is not working well. The changes in brain chemicals that occur when an SSRI type antidepressant is supplemented with risperidone (Risperdal®) will be studied. Spinal fluid is used to measure chemical levels of dopamine, serotonin, and other chemicals thought to be involved in depression. The study has potential to help understand and treat depression.

Timeline

Start: 2004-05
Primary completion: 2006-03
Completion: 2006-03

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Risperidone	Other / unclassified	—	—

Indications

No indication recorded.