drugset / Trial / NCT00179413

Study of Long-term Peg Intron vs. Colchicine in Non-responders.

NCT00179413

RandomizedParallel-groupOpen-labelPrevention

Summary

In this study Peg-Intron will be tested to see if it will give better results than Colchicine. At this time, there is currently no recommended maintenance treatment for patients who have failed to respond to Interferon/Rebetron/Peg Intron and have advanced fibrosis. The purpose of this study is to compare two treatments to slow down the progression of liver disease and to prevent liver failure and liver cancer. The treatment will not cure Hepatitis C, but is being evaluated to see if it can slow down disease progression.

Timeline

Start
2000-01-15
Primary completion
2009-12-31
Completion
2010-03-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Colchicine Small molecule 0.6 mg
Comparator Peginterferon alfa-2b Protein / enzyme biologic 0.5 ug/kg Subcutaneous