drugset / Trial / NCT00181181
The Effect of Statin Use on Vascular Function in Hypertensive Subjects
Phase 4
Terminated
24 enrolled
Johns Hopkins University
American Heart Association · collabProcris Pharmaceuticals · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
This research is being done to find if treatment with atorvastatin, a drug that reduces cholesterol, improves the function of blood vessels among people with high blood pressure. Adults with mildly high blood pressure, or who are taking medication for high blood pressure but are otherwise healthy may join, with the approval of their health care provider. The study period is 14-17 weeks. Approximately 50 to 60 subjects will take part in the study.
Timeline
- Start
- 2003-05
- Primary completion
- 2006-06
- Completion
- 2007-04
Outcome
Outcome not reported
Stopped: “Coronary flow by echo Doppler was obtainable in about 50% of subjects. The study was stopped early because of insufficient sample size to achieve adequate power”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | 80 mg | Oral |