Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease

Summary

The purpose of this study is to determine whether macrolide therapy is effective in treating patients hospitalized with asthma exacerbations or chronic obstructive pulmonary disease (COPD)exacerbations. We hypothesize that compared to placebo, maintenance therapy with macrolides, when added to usual care, a) improves respiratory symptoms, b) improves quality of life, c) reduces airway inflammation, d) reduces airflow obstruction, and e) decreases the rate of re-exacerbations.

Timeline

Start

2005-09

Primary completion

2006-07

Completion

2006-07

Drugs

Indications