Safety and Effectiveness Study of Maca Root to Treat Antidepressant-Induced Sexual Dysfunction

Summary

The purpose of this study is to determine the dose of Maca Root effective for the treatment of antidepressant-induced sexual dysfunction in patients with DSM-IV defined Major Depressive Disorder. We propose to carry out a dose-finding pilot study to determine the minimum effective dose of Maca Root. We hypothesize that patients who receive Maca Root will experience alleviation of their sexual dysfunction, and this effect will be more pronounced in those who receive higher doses of maca root.

Timeline

Start

2007-12

Primary completion

2010-06

Completion

2010-06

Outcome

Met primary endpoint

registry analysis (superiority test); Maca Root 1500mg vs Maca Root 3000mg; p = .016; Wilcoxon (Mann-Whitney) NCT00181961 ↗

Drugs

Indications