Phase I Intratumoral Dendritic Cell Immunotherapy in Thermally Ablated Liver Metastases

Summary

Up to twenty-two patients will be enrolled in this study to receive autologous dendritic cells (DCs) administered intratumorally into liver metastases following radiofrequency thermal ablation of those lesions. Patients will receive two vaccinations of DCs at monthly intervals. A dose escalation study of DCs will be included in this study in an attempt to define the maximum tolerated dose of administered DCs.

Timeline

Start

2004-01

Primary completion

2007-10

Completion

2007-10

Drugs

Indications