Seroquel in the Treatment of Dysphoric Hypomania in Bipolar II

Summary

1. The primary objective of this study is to examine the efficacy of quetiapine (Seroquel) in treatment of dysphoric hypomania in patients with Bipolar II disorder. 2. To evaluate the utility of Seroquel add-on treatment to decrease mixed depressive and hypomanic symptoms.

Timeline

Start

2008-08

Primary completion

2011-08

Completion

2011-08

Publications

• Results Suppes T, Ketter TA, Gwizdowski IS, Dennehy EB, Hill SJ, Fischer EG, Snow DE, Gonzalez R, Sureddi S, Shivakumar G, Cosgrove VE. First controlled treatment trial of bipolar II hypomania with mixed symptoms: quetiapine versus placebo. J Affect Disord. 2013 Aug 15;150(1):37-43. doi: 10.1016/j.jad.2013.02.031. Epub 2013 Mar 19.

Drugs

Indications