drugset / Trial / NCT00190515
A Trial Comparing Adjuvant Oral UFT/LV to 5-FU/l-LV in Stage III Colorectal Cancer (JCOG-0205-MF)
Phase 3
Completed
1101 enrolled
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
To evaluate the clinical effectiveness of oral UFT/LV comparing 5-FU/l-LV as adjuvant therapy for stage III colorectal cancer.
Timeline
- Start
- 2003-02
- Primary completion
- 2011-11
- Completion
- 2011-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Leucovorin | Small molecule | 75 mg | Intravenous |
| Subject | Leucovorin | Small molecule | 250 mg/m2 | Intravenous |
| Subject | UFT | Unknown | 300 mg/m2 | Oral |
| Comparator | fluorouracil | Small molecule | 500 mg/m2 | Intravenous |