drugset

drugset / Trial / NCT00190554

A Trial of Chemotherapy Before and After Surgery for Stage II,III Esophageal Squamous Cell Carcinoma

NCT00190554 ↗

Phase 3 Terminated 330 enrolled Japan Clinical Oncology Group Ministry of Health, Labour and Welfare, Japan · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

To determine whether chemotherapy before surgery makes better outcome than chemotherapy after surgery in patients with esophageal squamous cell carcinoma

Timeline

Start: 2000-05
Primary completion: 2004-05
Completion: 2009-05

Publications

Hirao M, Ando N, Tsujinaka T, Udagawa H, Yano M, Yamana H, Nagai K, Mizusawa J, Nakamura K; Japan Esophageal Oncology Group/Japan Clinical Oncology Group. Influence of preoperative chemotherapy for advanced thoracic oesophageal squamous cell carcinoma on perioperative complications. Br J Surg. 2011 Dec;98(12):1735-41. doi: 10.1002/bjs.7683. Epub 2011 Sep 14.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cisplatin	Other / unclassified	80 mg/m2	—
Subject	fluorouracil	Small molecule	800 mg/m2	—

Indications