Switching to Duloxetine From Other Antidepressants

Summary

A multicentre, randomised, open label study of out-patients with major depression who have failed to respond adequately to antidepressant treatment for their current episode of depression. The study compares outcomes associated with two methods of switching from current antidepressant to duloxetine

Timeline

Start

2004-08

Primary completion

—

Completion

2006-03

Outcome

Met primary endpoint

paper Criteria for noninferiority of the DS group to the STS group, which was the primary objective of the study, were met. PMID 18312043 ↗

Publications

• Perahia DG, Quail D, Desaiah D, Corruble E, Fava M. Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques. J Clin Psychiatry. 2008 Jan;69(1):95-105. doi: 10.4088/jcp.v69n0113.

Drugs

Indications