drugset

drugset / Trial / NCT00193349

Gleevec Combined With Camptosar Plus Paraplatin in Previously Untreated Extensive Stage Small Cell Lung Cancer

NCT00193349 ↗

Phase 2 Completed 60 enrolled SCRI Development Innovations, LLC Novartis · collab Pharmacia and Upjohn · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study will evaluate combination chemotherapy for patients with extensive stage small cell lung cancer combined with the potentially useful growth inhibiting effects of Gleevec.

Timeline

Start: 2002-09
Primary completion: 2007-12
Completion: 2007-12

Publications

Results Spigel DR, Hainsworth JD, Simons L, Meng C, Burris HA 3rd, Yardley DA, Grapski R, Schreeder M, Mallidi PV, Greco FA; Minnie Pearl Cancer Research Network. Irinotecan, carboplatin, and imatinib in untreated extensive-stage small-cell lung cancer: a phase II trial of the Minnie Pearl Cancer Research Network. J Thorac Oncol. 2007 Sep;2(9):854-61. doi: 10.1097/JTO.0b013e31814617b7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Carboplatin	Small molecule	4 unknown	—
Subject	Imatinib	Small molecule	600 mg	—
Subject	Irinotecan	Small molecule	60 mg/m2	—

Indications