Rt-PA Infusion Versus Catheter Exchange for Dialysis Catheter Malfunction Due to Fibrin Sheath

NCT00194181 ↗

Terminated 40 enrolled University of Pennsylvania Genentech, Inc. · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

Treating central venous dialysis catheter malfunction due to fibrin sheath formation with rt-PA(TPA)infusion will give equal patency rates in a more cost effective manner when compared to catheter exchange. Subjects are randomized to TPA infusion or catheter exchange and then followed for catheter function at the post treatment dialysis session, 30-day dialysis session and 60-day dialysis session. Costs and treatment results will be compared.

Timeline

Start: 2003-03
Primary completion: —
Completion: 2005-03

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	TPA	Unknown	—	Other

Indications

No indication recorded.