drugset / Trial / NCT00198120
Safety and Effectiveness of D-Cycloserine in Children With Autism
Phase 3
Completed
80 enrolled
Indiana University
National Alliance for Research on Schizophrenia and Depression · collabNational Institute of Mental Health (NIMH) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study will determine the effectiveness of D-cycloserine in reducing symptoms of autism in autistic children.
Timeline
- Start
- 2004-02
- Primary completion
- 2007-09
- Completion
- 2010-08
Publications
- Iffland M, Livingstone N, Jorgensen M, Hazell P, Gillies D. Pharmacological intervention for irritability, aggression, and self-injury in autism spectrum disorder (ASD). Cochrane Database Syst Rev. 2023 Oct 9;10(10):CD011769. doi: 10.1002/14651858.CD011769.pub2.
- Aye SZ, Ni H, Sein HH, Mon ST, Zheng Q, Wong YKY. The effectiveness and adverse effects of D-cycloserine compared with placebo on social and communication skills in individuals with autism spectrum disorder. Cochrane Database Syst Rev. 2021 Feb 14;2(2):CD013457. doi: 10.1002/14651858.CD013457.pub2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cycloserine | Small molecule | 1.7 mg/kg | — |