drugset / Trial / NCT00201344
A Phase III Study of Radiotherapy With or Without Adjuvant C/T in Advanced Stage Nasopharyngeal Carcinoma Patients
Phase 3
Terminated
320 enrolled
National Health Research Institutes, Taiwan
Kaohsiung Medical University · collabKaohsiung Veterans General Hospital. · collabMackay Memorial Hospital · collabNational Taiwan University Hospital · collabTaipei Veterans General Hospital, Taiwan · collabTri-Service General Hospital (TSGH) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
* To investigate the efficacy of adjuvant PFL chemotherapy after radiotherapy vs radiotherapy alone in AJC stage IV nasopharyngeal carcinoma patients. The endpoints of the study includes : overall survival, relapse free survival, distant metastasis and local-regional control rates. * To evaluate the toxicities of the two treatment methods.
Timeline
- Start
- 1994-11
- Primary completion
- —
- Completion
- 2000-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | — | — |
| Subject | Leucovorin | Small molecule | — | — |
| Subject | fluorouracil | Small molecule | — | — |