drugset / Trial / NCT00201396
A Multicenter Trial Comparing Induction C/T Followed by CCRT v.s. CCRT Alone in Stage IV Nasopharyngeal Carcinoma
Phase 3
Completed
480 enrolled
National Health Research Institutes, Taiwan
Chang Gung Memorial Hospital · collabChanghua Christian Hospital · collabChi Mei Medical Hospital · collabChina Medical University Hospital · collabChung Shan Medical University · collabKaohsiung Medical University Chung-Ho Memorial Hospital · collabKaohsiung Veterans General Hospital. · collabNational Taiwan University Hospital · collabTaipei Veterans General Hospital, Taiwan · collabTri-Service General Hospital (TSGH) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Investigate the effect of induction MEPFL chemotherapy followed by concurrent chemoradiotherapy (CCRT) on the disease control and survival in treatment of patients with advanced NPC.
Timeline
- Start
- 2003-08
- Primary completion
- 2009-08
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 30 mg/m2 | — |
| Subject | Epirubicin | Small molecule | — | — |
| Subject | Leucovorin | Small molecule | — | — |
| Subject | Mitomycin C | Other / unclassified | — | — |
| Subject | fluorouracil | Small molecule | — | — |