A Phase II Study of Capecitabine and Docetaxel in Previously Untreated Advanced Non-Small Cell Lung Cancer Patients

Summary

This study will determine the objective response rate in chemotherapy naive non-small cell lung cancer patients with advanced disease.

Timeline

Start

2004-12

Primary completion

2012-12

Completion

2013-04

Outcome

Missed primary endpoint

paper RR did not meet the pre-specified efficacy endpoint and the trial was stopped. PMID 23079156 ↗

Publications

• Results Bertino EM, Bekaii-Saab T, Fernandez S, Diasio RB, Karim NA, Otterson GA, Villalona-Calero MA. A phase II study of modulated-capecitabine and docetaxel in chemonaive patients with advanced non-small cell lung cancer (NSCLC). Lung Cancer. 2013 Jan;79(1):27-32. doi: 10.1016/j.lungcan.2012.09.013. Epub 2012 Oct 16.

Drugs

Indications