drugset / Trial / NCT00203320

TNF-Alpha Inhibition for Treatment of Alzheimer's Disease

NCT00203320

Phase 1 Completed 30 enrolled Tobinick, Edward Lewis, M.D.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

It is widely believed that inflammation contributes to the pathogenesis of AD. TNF has been implicated in both AD and neurological inflammation. Anti-TNF therapy is therefore surmised to be of potential benefit for treating AD.

Timeline

Start
2005-04
Primary completion
Completion
2006-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Etanercept Protein / enzyme biologic Other

Indications