drugset / Trial / NCT00203359

TNF-Alpha Inhibition for Treatment of Alzheimer's Disease

NCT00203359

Phase 1 Completed 15 enrolled Tobinick, Edward Lewis, M.D.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

It is widely believed that inflammation contributes to the pathogenesis of AD. TNF has been implicated in both AD and neurological inflammation. Anti-TNF therapy is therefore surmised to be of potential benefit for treating AD.

Timeline

Start
2004-09
Primary completion
Completion
2006-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Etanercept Protein / enzyme biologic Other

Indications