drugset / Trial / NCT00204451
Human Ovarian Follicular Dynamics and Emergency Contraception
Phase 4
Completed
40 enrolled
University of Saskatchewan
Canadian Institutes of Health Research (CIHR) · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
The researchers hypothesize that emergency contraception (EC) will initiate the changes associated with atresia or ovulatory failure at all stages of follicular development and that the image attributes associated with atresia will be similar regardless of the diameter of the dominant follicle when ovarian suppression is initiated. Second, changes associated with atresia may be observed, but ovulation of the dominant follicle is unimpeded.
Timeline
- Start
- 2005-07
- Primary completion
- —
- Completion
- 2006-06
Publications
- Background Pierson RA, Archer DF, Moreau M, Shangold GA, Fisher AC, Creasy GW. Ortho Evra/Evra versus oral contraceptives: follicular development and ovulation in normal cycles and after an intentional dosing error. Fertil Steril. 2003 Jul;80(1):34-42. doi: 10.1016/s0015-0282(03)00556-9.
- Background Baerwald AR, Adams GP, Pierson RA. A new model for ovarian follicular development during the human menstrual cycle. Fertil Steril. 2003 Jul;80(1):116-22. doi: 10.1016/s0015-0282(03)00544-2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Levonorgestrel | Small molecule | 0.5 mg | — |
| Subject | Levonorgestrel | Small molecule | 0.75 unknown | — |
| Subject | ethinyl estradiol | Small molecule | 50 mg | — |
Indications
No indication recorded.