drugset / Trial / NCT00205426

Natrecor for Pulmonary Hypertension in Lung Transplants

NCT00205426

Phase 4 Completed 7 enrolled University of Wisconsin, Madison
Non-randomizedSingle-groupOpen-labelPrevention

Summary

This study seeks to demonstrate that Natrecor® (nesiritide) is safe and effective and has a favorable hemodynamic profile in lung transplant recipients that will allow for the avoidance of inhaled nitric oxide (iNO) use. It is estimated that the use of nesiritide will decrease the otherwise historically mandated use of iNO by 50%, as compared to the necessity of iNO use by matched historical controls.

Timeline

Start
2005-08
Primary completion
2006-05
Completion
2006-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Nesiritide Protein / enzyme biologic 0.01 ug/kg