drugset / Trial / NCT00208065

Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers

NCT00208065

Phase 4 Completed 50 enrolled Clinvest Ortho-McNeil Neurologics, Inc. · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of this study is to evaluate histamine, CGRP and VIP levels in saliva as biological markers for activation of trigeminal and parasympathetic nerve fibers in various clinical presentations of primary headaches compared to allergic rhinosinusitis and control populations.

Timeline

Start
2004-05
Primary completion
2005-11
Completion
2005-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Pseudoephedrine Small molecule
Subject almotriptan Small molecule