Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
Summary
This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences). Myobloc is a purified and diluted form of botulinum toxin used medically to relax unwanted muscle spasms and movements. The aim of the study is to determine the feasibility of quantifying change in performance following treatment.
Timeline
- Start
- 2003-04
- Primary completion
- 2008-05
- Completion
- 2008-05
Outcome
Missed primary endpoint
registry analysis (superiority or other test); Note Errors (Related to Errors in Duration), Baseline vs Note Errors (Related to Errors in Duration), Post-injection; p =0.06; Wilcoxon (Mann-Whitney) NCT00208091 ↗
registry analysis (superiority or other test); Note Errors, Baseline vs Note Errors, Post-injection; p =0.23; Wilcoxon (Mann-Whitney) NCT00208091 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum Toxin Type B | Unknown | 500 iu | Intramuscular |