Higher Dose of Ramipril Versus Addition of Telmisartan-Ramipril in Hypertension and Diabetes

NCT00208221 ↗

Phase 3 Terminated 50 enrolled Montreal Clinical Research Institute

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine if a dose of ramipril combined with a normal dose of telmisartan 80 mg will be more effective than ramipril 20 mg in reducing microalbuminuria in hypertensive patients with diabetes.

Timeline

Start: 2006-08
Primary completion: —
Completion: 2007-06

Outcome

Outcome not reported

Stopped (Enrollment): “Not enough recruitment”

Publications

Natale P, Palmer SC, Navaneethan SD, Craig JC, Strippoli GF. Angiotensin-converting-enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic kidney disease. Cochrane Database Syst Rev. 2024 Apr 29;4(4):CD006257. doi: 10.1002/14651858.CD006257.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ramipril	Small molecule	10 mg	—
Subject	Ramipril	Small molecule	20 mg	—
Subject	Telmisartan	Other / unclassified	80 mg	—