drugset / Trial / NCT00209625

Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer

NCT00209625

Phase 1/2 Completed 23 enrolled Hokkaido Gastrointestinal Cancer Study Group
Non-randomizedSingle-groupOpen-labelTreatment

Summary

We performed a phase I/II study of CPT-11/5FU/l-LV in advanced colorectal cancer, to determine the optimal dose of CPT-11 and to estimate the safety and efficacy of this regimen

Timeline

Start
2000-04
Primary completion
Completion
2004-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule
Subject Leucovorin Small molecule
Subject fluorouracil Small molecule

Indications