drugset / Trial / NCT00209742
Randomized Phase III Adjuvant Study for Stage III Colorectal Cancer
Phase 3
Unknown
340 enrolled
Hokkaido Gastrointestinal Cancer Study Group
Hokkaido University Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
A randomized controlled study is conducted on patients with histological stage III colorectal cancer assigned to postoperative adjuvant therapy of uracil-tegafur plus leucovorin (UFT+LV), UFT+LV / UFT, or UFT+LV+PSK / UFT+PSK. The usefulness of the three regimens was evaluated by comparing the disease-free survival rate, overall survival rate, incidence and severity of adverse event, and quality of life.
Timeline
- Start
- 2005-04
- Primary completion
- 2012-12
- Completion
- 2012-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Krestin | Unknown | — | Oral |
| Subject | UFT | Unknown | — | Oral |
| Background | Leucovorin | Small molecule | — | Oral |