drugset / Trial / NCT00214110

Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS]

NCT00214110

Phase 2 Completed 100 enrolled University of Wisconsin, Madison
RandomizedParallel-groupSingle-blind

Summary

This is a single-center, phase 2 randomized clinical trial of tamoxifen on mean percent predicted isometric muscle strength in patients with amyotrophic lateral sclerosis (ALS). The purpose is to determine whether the triphenylethylenetamoxifen, used as adjuvant therapy in the treatment of breast cancer, can delay the loss of isometric muscle strength in ALS patients.

Timeline

Start
2001-01
Primary completion
Completion
2005-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tamoxifen Small molecule