Seroquel on Glucose Metabolism

Summary

The purpose of this study is to determine whether six months treatment with the antipsychotic medicine Seroquel (quetiapine) may affect the schizophrenic patient's glucose metabolism

Timeline

Start

2004-04

Primary completion

—

Completion

2005-10

Outcome

Met primary endpoint

paper was significantly lower for quetiapine versus olanzapine (t = 1.98, df = 377, p = .048). PMID 19358783 ↗

Publications

• Newcomer JW, Ratner RE, Eriksson JW, Emsley R, Meulien D, Miller F, Leonova-Edlund J, Leong RW, Brecher M. A 24-week, multicenter, open-label, randomized study to compare changes in glucose metabolism in patients with schizophrenia receiving treatment with olanzapine, quetiapine, or risperidone. J Clin Psychiatry. 2009 Apr;70(4):487-99. doi: 10.4088/jcp.08m04132. Epub 2009 Apr 7.

Drugs

Indications