drugset / Trial / NCT00214617
Effect of Crestor on Lipoprotein Metabolism in Humans
Phase 4
Completed
8 enrolled
Foundation for Atlanta Veterans Education and Research, Inc.
AstraZeneca · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The objective of this research is to understand how Crestor can effectively reduce the levels of the bad cholesterol, LDL, in blood. It is hypothesized that with a low dose, Crestor will facilitate the rate of removal of LDL from the blood. At the higher dose, the increased potency of Crestor is explained by a reduction in the production of LDL by the liver.
Timeline
- Start
- 2005-01
- Primary completion
- —
- Completion
- 2006-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rosuvastatin | Small molecule | 5 mg | — |
| Subject | Rosuvastatin | Small molecule | 40 mg | — |