drugset / Trial / NCT00216177

Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis

NCT00216177

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to establish whether RA patients with moderate to severe disease activity with unsustainable response to infliximab 3 mg/kg every 8 weeks have better efficacy with adalimumab 40 mg s.c. eow compared to infliximab 3 mg/kg i.v. every 6 weeks.

Timeline

Start
2005-09
Primary completion
2009-01
Completion
2009-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Adalimumab Monoclonal antibody 40 mg Subcutaneous
Subject Infliximab Monoclonal antibody 3 mg/kg Intravenous

Indications