drugset / Trial / NCT00218062
Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals
Phase 2
Completed
73 enrolled
The University of Texas Health Science Center, Houston
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found. The purpose of this study is to examine the effects of d-amphetamine and modafinil, when given alone and in combination, in treating cocaine dependent individuals.
Timeline
- Start
- 2006-03
- Primary completion
- 2012-01
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dextroamphetamine | Small molecule | 30 mg | — |
| Subject | Dextroamphetamine | Small molecule | 60 mg | — |
| Subject | Modafinil | Small molecule | 200 mg | — |
| Subject | Modafinil | Small molecule | 400 mg | — |