drugset / Trial / NCT00218153
Naltrexone Augmentation of Nicotine Patch Therapy - 1
RandomizedParallel-groupDouble-blindTreatment
Summary
Naltrexone Augmentation of Nicotine Patch Therapy
Timeline
- Start
- 2000-11
- Primary completion
- —
- Completion
- 2004-04
Publications
- King AC, Cao D, Zhang L, O'Malley SS. Naltrexone reduction of long-term smoking cessation weight gain in women but not men: a randomized controlled trial. Biol Psychiatry. 2013 May 1;73(9):924-30. doi: 10.1016/j.biopsych.2012.09.025. Epub 2012 Nov 22.
- O'Malley SS, Krishnan-Sarin S, McKee SA, Leeman RF, Cooney NL, Meandzija B, Wu R, Makuch RW. Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation. Int J Neuropsychopharmacol. 2009 Jun;12(5):589-97. doi: 10.1017/S146114570800936X. Epub 2008 Sep 17.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | 25 mg | Oral |
| Subject | Naltrexone | Small molecule | 50 mg | Oral |
| Subject | Naltrexone | Small molecule | 100 mg | Oral |