drugset

drugset / Trial / NCT00219063

A Clinical Study to Compare an Aliskiren Based Hypertensive Regimen With a Ramipril Based One Followed by a Randomized Withdrawal.

NCT00219063 ↗

Phase 3 Completed 844 enrolled Novartis

RandomizedParallel-groupDouble-blindTreatment

Summary

To compare the aliskiren regimen versus the ramipril regimen on reduction in Blood Pressure.

Timeline

Start: 2005-02
Primary completion: 2006-03
Completion: 2006-03

Publications

Results Andersen K, Weinberger MH, Egan B, Constance CM, Ali MA, Jin J, Keefe DL. Comparative efficacy and safety of aliskiren, an oral direct renin inhibitor, and ramipril in hypertension: a 6-month, randomized, double-blind trial. J Hypertens. 2008 Mar;26(3):589-99. doi: 10.1097/HJH.0b013e3282f3ad9a.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Aliskiren	Small molecule	300 mg	Oral

Indications