drugset / Trial / NCT00225550
A Study of the Safety and Effects of ADH-1 Given Daily to Subjects With Solid Tumors
Non-randomizedSingle-groupOpen-labelTreatment
Summary
N-cadherin, a protein involved in blood vessel cell binding, is increased as cancer progresses, and is on the surface of many tumor cells. ADH-1 blocks N-cadherin. This study will test the safety and effects of ADH-1 in subjects with incurable, solid tumors with a protein biomarker called N-cadherin. This study will identify the amount of ADH-1 that subjects can tolerate.
Timeline
- Start
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- Primary completion
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- Completion
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Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ADH-1 | Protein / enzyme biologic | — | Intravenous |