drugset / Trial / NCT00231569
Dose-escalating Safety Study in Subjects on Stable Statin Therapy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The aim of this study is to assess the safety of varying doses of ISIS 301012 in subjects on Stable statin therapy.
Timeline
- Start
- 2005-09
- Primary completion
- 2007-06
- Completion
- 2007-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | mipomersen | Antisense oligonucleotide | 30 mg | Subcutaneous |
| Subject | mipomersen | Antisense oligonucleotide | 100 mg | Subcutaneous |
| Subject | mipomersen | Antisense oligonucleotide | 200 mg | Subcutaneous |
| Subject | mipomersen | Antisense oligonucleotide | 300 mg | Subcutaneous |
| Subject | mipomersen | Antisense oligonucleotide | 400 mg | Subcutaneous |