drugset / Trial / NCT00232492
Ketamine on Acute Pain in Females and Males
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of the study is to determine whether equal subanesthetic doses of racemic ketamine is equally effective on females and males after surgical removal of third molars
Timeline
- Start
- 2005-01
- Primary completion
- 2006-11
- Completion
- 2006-11
Publications
- Background Oye I, Mathisen LC. The effect of CPP in neurogenic pain: inhibition of spinal or cortical NMDA receptors? Pain. 1993 Jun;53(3):358. doi: 10.1016/0304-3959(93)90234-G. No abstract available.
- Background Øye I, Hustveit O, Maurset A, Ratti Moberg E, Paulsen O, Skoglund LA. The chiral forms of ketamine as probes for NMDA receptor functions in humans. In: NMDA receptor related agents: Biochemistry, pharmacology and behaviour. Kameyama T, Domino E (eds). NPP Books, Ann Arbor, 1991.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | 0.1 mg/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 0.3 mg/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | Intravenous |