drugset / Trial / NCT00234416

IRESSA Combined With Radiotherapy & Gemcitabine as First-Line Treatment in Locally Advanced Pancreatic Cancer

NCT00234416

Phase 1/2 Completed 45 enrolled AstraZeneca
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary objective of the trial is to identify the dose of gemcitabine given as a 2-hour intravenous (iv) infusion that can be administered in combination with ZD1839 250 mg once daily and a standard course (45 Grays \[Gy\]) of radiotherapy in patients with locally advanced, unresectable pancreatic cancer.

Timeline

Start
2002-08
Primary completion
Completion
2005-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Gefitinib Small molecule 250 mg
Subject Gemcitabine Small molecule Intravenous