drugset / Trial / NCT00240513
Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin
RandomizedParallel-groupSingle-blindTreatment
Summary
The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby increasing the therapeutic effect of the oral antibiotic.
Timeline
- Start
- 2004-08
- Primary completion
- 2006-12
- Completion
- 2006-12
Outcome
Outcome not reported
Stopped (Enrollment): “Too much difficulty recruiting and retaining patients, PI decided to stop.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Minocycline | Small molecule | 100 mg | Oral |
| Subject | Tretinoin | Unknown | 0.01 % | Topical |