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drugset / Trial / NCT00240513

Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin

NCT00240513 ↗

Phase 4 Terminated 38 enrolled Derm Research @ 888 Inc. Stiefel, a GSK Company · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby increasing the therapeutic effect of the oral antibiotic.

Timeline

Start
2004-08
Primary completion
2006-12
Completion
2006-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Minocycline Small molecule 100 mg Oral
Subject Tretinoin Small molecule 0.01 % Topical

Indications

acne