A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting

Phase 2 Completed 318 enrolled Johnson & Johnson Consumer and Personal Products Worldwide

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of the study is to determine if ibuprofen in combination with pseudoephedrine HCl in the treatment of nightime bedwetting in children is more effective than each drug alone and if the individual drugs are more effective than placebo.

Timeline

Start: —
Primary completion: —
Completion: 2002-11

Publications

Caldwell PH, Codarini M, Stewart F, Hahn D, Sureshkumar P. Alarm interventions for nocturnal enuresis in children. Cochrane Database Syst Rev. 2020 May 4;5(5):CD002911. doi: 10.1002/14651858.CD002911.pub3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ibuprofen	Small molecule	12.5 mg/kg	Oral
Subject	Pseudoephedrine	Small molecule	15 mg	Oral
Subject	Pseudoephedrine	Small molecule	30 mg	Oral

A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting

Summary

Timeline

Publications

Drugs

Indications