drugset / Trial / NCT00243035

Tipifarnib and Bortezomib in Treating Patients With Relapsed Multiple Myeloma

NCT00243035

Phase 1/2 Terminated 64 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial is studying the side effects and best dose of tipifarnib when given together with bortezomib and to see how well they work in treating patients with relapsed multiple myeloma. Tipifarnib and bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving tipifarnib together with bortezomib may kill more cancer cells.

Timeline

Start
2005-08
Primary completion
2007-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule Intravenous
Subject tipifarnib Small molecule Oral

Indications