drugset / Trial / NCT00247572

Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories

NCT00247572

Phase 2 Completed 12 enrolled New River Pharmaceuticals
RandomizedCrossoverDouble-blindTreatment

Summary

This research is being done to evaluate if NRP 104 is a safe drug. The other purpose is to learn if NRP104, when injected into a vein, produces a high and any other effects like amphetamine and other stimulant drugs that are abused. This information will give some indication if NRP104 can be abused. Healthy people, between the ages of 18 and 55 with histories of substance abuse that include stimulant drugs, may join. Amphetamines are drugs that are used most often to treat attention deficit hyperactivity disorder (ADHD) in children, to treat narcolepsy (excessive sleepiness) and for weight loss.

Timeline

Start
2005-09
Primary completion
Completion
2005-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Lisdexamfetamine Dimesylate Small molecule 25 mg Intravenous
Subject Lisdexamfetamine Dimesylate Small molecule 50 mg Intravenous