A Comparison of the Effectiveness and Safety of Injectable Risperidone With That of Risperidone Tablets in the Treatment of Patients With Chronic Schizophrenia

Summary

The primary purpose of the study is to show that treatment with an injectable formulation of risperidone is not less effective than and has a similar safety profile to risperidone tablets in patients with chronic schizophrenia.

Timeline

Start

2000-01

Primary completion

—

Completion

2000-12

Outcome

Met primary endpoint

paper According to a noninferiority analysis, the two treatments showed comparable efficacy in total PANSS scores over the short-term. PMID 15572280 ↗

Publications

• Results Chue P, Eerdekens M, Augustyns I, Lachaux B, Molcan P, Eriksson L, Pretorius H, David AS. Comparative efficacy and safety of long-acting risperidone and risperidone oral tablets. Eur Neuropsychopharmacol. 2005 Jan;15(1):111-7. doi: 10.1016/j.euroneuro.2004.07.003.

Drugs

Indications